We have addressed the static clustering problem in a Maximum Entropy Principle framework and developed algorithms that are scalable and amenable to
distributed implementation. The MEP framework was augmented with additional constraints for addressing the issues of scalability and computational
efficiency. The proposed algorithm outperforms the non-scalable algorithm in terms of computation time and handles much larger datasets.
We have successfully implemented these scalable algorithms for solving the library selection problems in combinatorial
drug-discovery, by simultaneously addressing the key issues of diversity, representativeness, inclusion/exclusion
and scalability. Similar framework is also used for solving the state-space discretization problem in quantized
control.
Presently, we are working on clustering and coverage problems associated with moving objects.
We have developed a Maximum Entropy based algorithm for solving this dynamic locational optimization problem. Our emphasis is on hierarchical
clustering algorithms that are designed to avoid local minima and insensitive to initial placement of clusters. The algorithm has been addressed in
a control-theoretic framework to ensure that the coverage metric (clustering cost function) is continuously improved. Bifurcation conditions for the
underlying optimization problem lead to its hierarchical structure.
Publications
J. Chem. Inf. Model., 48, 1, 27 - 41, 2008.
Proc. of American Control Conference, 2008.
Proc. of American Control Conference, 516-521, 2007.
Proc. of American Control Conference, 3092-3097, 2006.
Proc. of American Control Conference, 979- 984 vol. 2, 2005.
Proc. of American Control Conference, 5238- 5243 vol.6, 2004.
Ph.D. Prelim Report
Ph.D. Qualifying Exam Presentation
M.S. Thesis
Talks, Presentations & Reports
(awarded best paper in session)
(awarded best paper in session)
Report [pdf]
Graduate Coursework
Research
Research Focus
Project 1[pdf]
Project2
[pdf] Paper Review
[pdf]